PHYTOADAPTOGENES INCREASE ELECTRICAL STABILITY OF HEART DURING ISCHEMIA-REPERFUSION AND POSTINFARCTION CARDIOFIBROSIS

Maslov Leonid Nikolaevich, Arbuzov Aleksandr Gennadyevich, Bashelkhanova Tuyana Stepanovna, Burkova Valentina Nikolaevna, Safronov Sergey Mikhaylovich

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It has been established that the course administration (5 days at a dose of 16 mg/kg per os) of extracts of Aralia mandshurica or Rhodiola rosea decreased the incidence of ischemic and reperfusion ventricular arrhythmias during a 10-min coronary artery occlusion and a 10-min reperfusion. Extracts of Eleutherococcus senticosus, Leuzea carthamoides and Panax ginseng had no effect on the incidence of ischemic and reperfusion arrhythmias. Chronic administration of Aralia, Rhodiola and Eleutherococcus increased the ventricular fibrillation threshold (VFT) value in rats with postinfarction cardiosclerosis. Ginseng and Leuzea did not affect the VFT in rats with postinfarction cardiosclerosis.

Keywords: phytoadaptogenes, heart, ischemia, reperfusion, cardiosclerosis, arrhythmias

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( 1.37 MB ) ( 1.28 MB )

Issue: 3, 2009

Rubric: Cardiology and Functional Diagnostics

Pages: 16 — 20

Downloads: 1089